(a) Menaquinone-7

As described above, Menaquinone-7 suppresses the overactive enzyme that regulates flushing and blushing — reducing both their frequency and intensity, and actively dialing back rosacea triggers and flares.

(b) Sulforaphane — Enzyme-Activated, Enteric-Coated Formula

Sulforaphane is one of the most powerful nutraceuticals for rosacea treatment. Rosadyn+ uses a next-generation enzyme-activated version with an enteric coating — dramatically increasing its bioavailability and protecting it from stomach acid so it can do its job where it counts most.

Once absorbed, sulforaphane penetrates directly into the cell nucleus of blood vessels and skin cells to deliver three critical actions: it inhibits uncontrolled blood vessel growth by up to 83% in clinical studies; it blocks three key inflammatory substances driving rosacea progression — NF Kappa Beta, Inflammatory Cytokines, and Dilator Prostaglandins; and it activates Antioxidant Response Elements (AREs) that clinical studies confirm are defective in rosacea sufferers — a deficiency that directly fuels symptoms and triggers.

(a) Maqui Berry

Sourced from the tropical forests of Chile, Maqui Berry earned the title of #1 Superfruit and natural anti-inflammatory in 2015 — and for good reason. It's the most potent antioxidant ever tested, scavenging free radicals at 400% the rate of Acai berry.

That's a big deal for rosacea sufferers. Inflammatory free radicals drive every symptom and trigger — damaging skin cells, intensifying flushing, and breaking down the skin's protective outer layer. Maqui Berry's unique Delphinol molecules neutralize all free radicals known to be active in rosacea, making it one of the most powerful anti-inflammatory ingredients available for this condition.

(b) Pomegranate Berry

Ranked the #2 highest-rated antioxidant studied to date, Pomegranate is widely praised by Naturopathic Physicians as the gold standard anti-acne supplement — thanks to its unique molecules called punicosides.

Punicosides (40% standardized) normalize the skin's immune system and suppress immune-mediated inflammation. This blocks neutrophils from migrating to the epidermis, directly reducing the formation of rosacea papules and pustules. It also reduces inflammation around sebaceous glands — potentially addressing a connection to demodex. On top of that, pomegranate helps clear regular acne by blocking the hormones that trigger whiteheads and blackheads in the most active pore areas of the face.

(c) Mangosteen Berry

Derived from the rind of the tropical Mangosteen, this superfruit contains xanthones — some of the most powerful and skin-specific anti-inflammatory molecules known to science.

Xanthones zero in on inflamed skin cells by following the inflammatory cell adhesion molecules present in rosacea skin. Along the way, they clear those adhesion molecules, actively breaking the acne rosacea cycle. Mangosteen also speeds up skin healing by triggering the release of zinc-, selenium-, and sulfur-based healing molecules from adjacent skin cells — accelerating the clearance of stubborn papules and pustules.

(d) Olive Leaf Extract (Olea Europea, 15% Oleuropein)

Olive Leaf Extract produces Oleuropein — a patented extract from a select Italian olive variety, exceptionally rich in polyphenols, bioflavonoids, antioxidants, and skin-beautifying biochemicals. For rosacea sufferers, it's an essential ingredient.

Oleuropein acts as the "glue" that bonds collagen and elastin together, protecting the structural integrity of rosacea-affected skin. It also shields hyaluronic acid — a key connective tissue component and one of the body's most effective natural moisturizers — giving Olive Leaf Extract its ability to hydrate skin from within. As a bonus, it's a potent blocker of several Matrix Metalloproteinases (MMPs) — enzymes known to drive rosacea inflammation and vascular breakdown.